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Scientific Manager - Immunology (Nanostring, Exome, RNA, CHIP)

Company: MD Anderson Cancer Center
Location: Houston
Posted on: January 16, 2022

Job Description:

The Immunology department at MD Anderson Cancer Center seeks to determine the fundamental cellular and molecular mechanisms of a wide range of processes by which the body recognizes and eliminates pathogens and use these findings to unleash the patient's own immune system against previously treatment-resistant cancers. Treating the immune system rather than the cancer itself, the therapeutics developed are applicable to many cancers.




  • Supervises computational scientists to perform data analysis on a variety of projects that include analysis, integration and interpretation of diverse data types for example, NGS datasets; single cell sequencing, exome sequencing, RNA-seq, ATAC-seq, TCR/BCR-seq, Array datasets; microarray, protein arrays, SNP arrays, gene and protein expression datasets; Nanostring and CYTOF, Image and spatial analysis datasets; CODEX, DSP and other experimental data in the setting of immunotherapy.
  • Develops and manages data analysis and data visualization tools and applies novel tools for data integration across diverse platforms which includes genomic, proteomic, clinical meta data and others as needed.
  • Leads and trains the bioinformatics group to investigate state-of-the-art statistical analysis tools and apply to multiple big datasets as needed.
  • Manages data storage and reporting for the platform and publications as needed.
  • Effectively presents data to the pharmaceutical or internal collaborators as needed.
  • Independently searches literatures in the field of bioinformatics and statistics, writes the bioinformatics analysis and methods section for manuscripts and grant applications.
  • Other duties as assigned.
    • Participates in all administrative activities and the recruitment of new computational scientists to IMT, including recruitment, education, evaluation and retention of competent and qualified personnel.
      • Overviews the hardware and software requirements for high throughput data storage and analysis.
      • Recommends, schedules, and performs software improvements and upgrades.
      • Provides bioinformatics consultation for clinical and biological research projects.
      • Works closely with clinical scientists and provides custom solutions for sequencing, gene expression, proteomics and other data to expedite scientific project.#LI-MDACC


        Required: Bachelor's degree in one of the basic sciences.

        Preferred: Master's degree or PhD in one of the basic sciences.


        Required: Seven years relevant research experience to include two years in a supervisory/managerial capacity. With preferred Masters degree, five years of required experience to include two years in a supervisory/managerial capacity and with preferred PhD, three years of required experience to include two years in a supervisory/managerial capacity. Successful completion of the LEADing Self Accelerate program may substitute for one year of required supervisory or management experience.

        Preferred: Nanostring analysis, exome sequencing, RNA-seq, CHIP-Seq, microarray and other experimental data in the setting of immunotherapy. Bioinformatics consultation for clinical and biological research projects.


        Required: Must pass pre-employment skills test as required and administered by Human Resources.

        Additional Information
        • Requisition ID: 145862
        • Employment Status: Full-Time
        • Employee Status: Regular
        • FLSA: exempt and not eligible for overtime pay
        • Work Week: Days
        • Fund Type: Soft
        • Remote Work: Hybrid Onsite/Remote
        • Pivotal Position: Yes
        • Minimum Salary: US Dollar (USD) 87,000
        • Midpoint Salary: US Dollar (USD) 130,000
        • Maximum Salary : US Dollar (USD) 173,000
        • Science Jobs: Yes

Keywords: MD Anderson Cancer Center, Houston , Scientific Manager - Immunology (Nanostring, Exome, RNA, CHIP), Healthcare , Houston, Texas

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