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Research Group Leader - Immunology (Bioinformatics)

Company: The University of Texas M. D. Anderson Cancer Cent
Location: Houston
Posted on: January 26, 2023

Job Description:

The Immunology department at MD Anderson Cancer Center seeks to determine the fundamental cellular and molecular mechanisms of a wide range of processes by which the body recognizes and eliminates pathogens and use these findings to unleash the patient's own immune system against previously treatment-resistant cancers. Treating the immune system rather than the cancer itself, the therapeutics developed are applicable to many cancers.



Data Analysis

  • Develop algorithms and novel strategies to analyze and visualize large scale multi-omics data from internal and publicly available datasets to enable biomarker identification.
  • Formulate and guide feasibility analyses of new assays in conjunction with assay development.
  • Present data analyses to pharmaceutical and MD Anderson collaborators.
  • Oversee the generation of detailed and well-organized documentation of analysis and methods.
  • Compose bioinformatics analysis and methods sections for manuscripts and grant applications.
  • Manage data storage and reporting for the platform and publications as needed.
  • Explore and implement cutting-edge approaches to analysis of datasets.
  • Independently search literature to explore new fields of bioinformatics and statistics research to merge with immunology research.
  • Compose bioinformatics analysis and methods sections for manuscripts and grant applications.
  • Ensure hardware and software requirements are outlined and met for high throughput data storage, software upgrades, and analysis.
  • Provide bioinformatics consultation for clinical and biological research projects.
  • Present data analyses to pharmaceutical and MD Anderson collaborators.
  • Work closely with clinical researchers and others to provide custom solutions for sequencing, gene expression, proteomics and other data to expedite scientific projects


    • Contribute to a highly collaborative work environment toward the research goals of the Immunotherapy Platform, participating in brainstorming, planning, and data sharing sessions.
    • Collaborate with peer scientists from cross-functional teams to analyze and interpret complex large datasets and communicate findings.


      • Lead and mentor a team of qualified computational scientists; Provide training and education in statistical and bioinformatics analysis of multi-omics datasets (spatial transcriptomics such as CODEX, DSP, single cell sequencing including TCR/BCR sequencing, ATAC-seq, whole exome sequencing) to support target discovery, and translational research.
      • Recruit, develop and mentor junior scientists, as needed.


        Required: PhD in one of the natural sciences or related field or Medical degree.



        Required: Seven years experience of relevant research experience in laboratory to include three years of managerial experience. Successful completion of the LEADing Self Accelerate program may substitute for one year of required supervisory or management experience.


        It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

        Additional Information
        • Requisition ID: 153695
        • Employment Status: Full-Time
        • Employee Status: Regular
        • Work Week: Days
        • Minimum Salary: US Dollar (USD) 112,000
        • Midpoint Salary: US Dollar (USD) 140,000
        • Maximum Salary : US Dollar (USD) 168,000
        • FLSA: exempt and not eligible for overtime pay
        • Fund Type: Soft
        • Work Location: Remote (within Texas only)
        • Pivotal Position: Yes
        • Science Jobs: Yes

Keywords: The University of Texas M. D. Anderson Cancer Cent, Houston , Research Group Leader - Immunology (Bioinformatics), Healthcare , Houston, Texas

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