R&D - Scientist-Downstream Processing

Company: Impellam Group N.A.
Location: Houston
Posted on: May 4, 2021

Job Description:

Process Development Scientist IIIWork in a high performing team with the goal of driving innovation in the development of novel scalable viral vector production platforms for use in in vivo and ex vivo gene therapy applications. The successful candidate will provide support in identifying, developing and implementing viral vector downstream purification technologies, using resources internal and external to Lonza in order to support in creating scalable robust solutions to viral production bottlenecks. This hands-on downstream bioprocess scientist will design and execute experiments, develop metrics for evaluating results and technologies and procure equipment. The incumbent will be responsible for acquiring, analyzing, and communicating experimental data in cross-functional fashion.Key responsibilities:Perform planned experimental work, including but not limited to downstream purification of cell harvests (cell lysis, clarification, filtration, TFF, chromatography) and analytical work associated with the project. Interprets results and evaluates next steps in experimental design. Organize and plan assigned daily activities to ensure timely completion of assignmentsSupports design and execution of experiments, including data analysis and communication. Obtains and analyzes experimental dataMaintains accurate and up to date records, including appropriate lab notebook recordings. Capable of achieving deliverables on-time and high-quality.Leads and/or Assists in writing and revising technical documents including lab Standard Operating Procedures, testing protocols and reports.Maintains stocks of lab supplies and reagents and performs other assigned lab organization duties as needed.Prepares and regularly updates documentation required by other Departments of the company (such as Quality Control and Quality Assurance) or presentations to successfully complete assigned projects.Perform other duties as assigned.Key requirements:Ph.D or MS with entry level experience.Preferred area of study: protein and/or viral vector purification, isolation/purification of biomacromolecules/biomolecules, chemistry with focus on/ experience with the purification of water-soluble compounds.Expertise in small scale lab experiments and assay execution. Hands-on experience operating chromatographic systems (Akta Explorer, Akta Pure or similar) and associated software required. Hands-on experience with TFF preferredExcellent written and oral communication skills and the ability to thrive in a multi-disciplinary, collaborative environment are essential. Independence and strong work ethic are a must.Positive attitude with willingness and agility to change priorities per the business needs. Problem solving, innovative outlook. Creative and collaborative. Takes ownership/leads. SRG is an Equal Opportunity Employer - All qualified applicants will receive consideration without regard to race, color, religion, gender, national origin, age, disability, veteran status, or any other factor determined to be unlawful under applicable law.

Keywords: Impellam Group N.A., Houston , R&D - Scientist-Downstream Processing, Other , Houston, Texas